首批人类胚胎在美国进行编辑，这在创造“设计婴儿”上迈出了富有争议的一步 [英国媒体]

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A controversial technique that lets scientists 'edit' genes in a human embryo has been successfully used for the first time in the US.

在美国首次成功应用了一个有争议的技术，允许科学家“编辑”人类胚胎中的基因。

The effort involved changing the DNA of a group one-cell human embryos with the 'cut and paste' gene-editing technique known as CRISPR.

通过一种被称作CRISPR（Clustered regularly interspaced short palindromic repeats，常间回文重复序列丛集--译者注）的基因编辑技术进行“剪切和粘贴”来尝试修改一组单个人类胚胎细胞。

The technique means the next generation may benefit from powerful gene therapies that can dexe or repair flawed genes.

该技术意味着下一代可能受益于强大的基因治疗，可以去除或修复有缺陷的基因。

It could act as a golden bullet for diseases like cancer HIV and genetic conditions such as Huntington's disease. 

它可以作为治疗诸如癌症、HIV和遗传疾病如亨廷顿氏病等疾病的低费高效解决方案。

But some countries have signed a convention prohibiting the practice based on concerns it could be used to create 'designer babies'.

但是一些国家已经签署了一项禁止这种做法的公约，该公约基于人们担心它可以用来制造“设计婴儿”。

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The research led by Shoukhrat Mitalipov head of OHSU's Center for Embryonic Cell and Gene Therapy involves a technology known as CRISPR.

 由美国俄勒冈洲健康与科学大学胚胎细胞和基因治疗中心的主任舒克拉特·米塔利普夫所领导的这项研究涉及到一门被称作基因编辑的技术。

Scientists in China have previously published similar studies with mixed results.

中国科学家以前发表过类似的研究，结果喜忧参半。

But many are opposed to these types of experiments over concerns it could be used to create 'designer babies'.

但是许多人反对这些类型的实验，它可能用来制造“设计婴儿”。

The US intelligence community last year labelled CRISPR a potential 'weapon of mass destruction.'

去年，美国情报界将基因编辑技术贴上了潜在的“大规模毁灭性武器”的标签。

In recent days the US Defense Advanced Research Projects Agency (DARPA) created the Safe Genes program in order to better understand how these gene editing technologies work. 

最近几天，美国国防部高级研究计划署（DARPA）创建了安全基因计划，以便更好地了解这些基因编辑技术的运作。 

And in December 2015 Scientists and ethicists held and an international meeting held at the National Academy of Sciences (NAS) in Washington.

2015年12月在华盛顿科学研究院（NAS）举行过一场科学家和伦理学家参加的国际性会议。

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They said it would be 'irresponsible' to use gene editing technology in human embryos for therapeutic purposes.

他们普遍认为为了治疗疾病在人类胚胎中使用基因编辑技术是不负责任的行为。

Researchers from Oregon Health and Science University (OHSU) in Portland carried out the study according to MIT's Technology Review. 

据麻省理工科技评论杂志的报道，位于波特兰市的俄勒冈健康与科技大学的研究人员开展了这项研究

So far three previous reports of editing human embryos were all published by scientists in China.

到目前为止，在人类基因编辑技术领域的前三项研究成果均由中国科学家发表（骄傲~）。

But this experiment is believed to have broken new ground in the number of embryos experimented upon.

但这次实验在实验胚胎数量上有了新突破

None of the embryos were allowed to develop for more than a few days according to sources familiar with the study.

根据消息人士的说法，这些胚胎只被允许培育几天时间。

The research led by Shoukhrat Mitalipov head of OHSU's Center for Embryonic Cell and Gene Therapy involves a technology known as CRISPR.

领导这次研究实验的舒克拉特·米塔利波夫，作为俄勒冈大学胚胎细胞与基因治疗学中心的组长，采用了一种名为CRISPR的技术。

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This has opened up new frontiers in genetic medicine because of its ability to modify genes quickly and efficiently.

这为基因医学开辟了新的领域，因为它能够迅速有效地修改基因。

CRISPR works as a type of molecular scissors that can sextively trim away unwanted parts of the genome and replace it with new stretches of DNA.

CRISPR(基因编辑技术）作为一种分子剪刀可以剪去不需要的基因组部分以及用新的DNA片段加以替换。

Results of the peer-reviewed study are expected to be published soon in a scientific journal according to OHSU spokesman Eric Robinson.

根据 OHSU（俄勒冈卫生科技大学）的发言人埃里克·罗宾逊所说，同行审查的研究结果预计将在一个科学期刊上出版。

Speaking to Technology Review a scientist familiar with the project said: 'It is proof of principle that it can work. 

科技评论中一个熟悉此计划的科学家说：“它证明了这个原理可以起作用。”

'They significantly reduced mosaicism. 

它们明显地减少了镶嵌性。

'I don't think it's the start of clinical trials yet but it does take it further than anyone has before.' 

“我认为它还不是临床试验的开始但是它比之前的任何一个计划都更进一步。”

Scientists in China have previously published similar studies with mixed results. 

中国科学家已经发表过的类似研究中伴随着复杂的结果。

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But many are opposed to these types of experiments including religious civil society and biotech groups.

但是许多人反对这种类型的实验包括宗教民间团体和生物科技集团。

The US intelligence community last year labelled CRISPR a potential 'weapon of mass destruction.'

美国情报机构去年给‘CRISPR’（基因编辑技术）贴上了一个潜在的“大规模杀伤性武器”的标签。

In recent days the US Defense Advanced Research Projects Agency (DARPA) created the Safe Genes program in order to better understand how these gene editing technologies work. 

最近几天，美国国防部高级研究计划局（DARPA)创建了安全基因计划，为了更好地理解这些基因编辑技术是如何工作的。

And in December 2015 Scientists and ethicists held and an international meeting held at the National Academy of Sciences (NAS) in Washington.

在2015年12月，科学家和伦理学家在华盛顿的国家科学院（NAS）举行了一场国际会议。

They said it would be 'irresponsible' to use gene editing technology in human embryos for therapeutic purposes such as to correct genetic diseases until safety and efficacy issues are resolved.

他们说在人类胚胎中使用基因编辑技术比如纠正遗传疾病是不负责任的，除非安全和疗效问题得到解决。


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Tony Bush
they can only edit not add new information to DNA. never proved or witnessed it happend in nature. if new information added into DNA is never proven evolution is never proven.

他们只能编辑而不是给DNA添加新信息。这种做法从来没有在自然界被证实或目睹。如果DNA加入了新信息，这是从来没有被验证过的事情。

electric universe
Not religious but why do pro genetic engineering brigade always resort to religion. You dont need a god to tell you this is incorrect thinking and will eventually be used as a tool to oppress humanity. Cant people see further than their nose ?scientists are nobodys friends there just uncontrolled egos who act out their ego driven fantasies regardless of consequences

不是宗教，但为什么专业基因工程队伍总是诉诸宗教？ 你不需要一个上帝来告诉你这是不正确的想法，最终它将被用作压迫人类的工具。 他们不能有点远见么？科学家从来不是任何人的朋友，他们总是自我满足，不计后果的追逐他们自我实现的梦幻天国。

Nathan James Crowle -> electric universe
Lol nxt ya gonna b spouting on about the evils of electricity....... WHY should people suffer needlessly because of people like u.... Can you give me a coherent reason why it's incorrect thinking?? I suspect not.. instead your imposing your outraged ethics on others. I do not agree with you at all

Lol  接下来你是不是要喷一下电的危害……为什么人们要因为像你这样的人不必要地受苦……你能给我一个条理分明的原因，为什么它是错误的想法？我怀疑你给不了。相反，你把你另人愤怒的伦理道德观强加给别人。我根本不同意你的意见

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Kim Jong-uns Stylist
Designer babies? Every time a couple meet enter a relationship together and have children they've made a calculated decision to do so based on the genetic traits the other person possesses. Any artificial method simply offers increased choice and accessibility. 

设计婴儿？每当一对夫妇相遇，一起维系一段关系并生下孩子时，他们就根据对方的遗传特征做出了一个合理的决定。任何人工方法都只是提供了更多的选择和未来可能。

Carpejugulum
I genuinely fail to see why the god bothering brigade prefer to see children born with crippling genetic diseases rather than accept curing these diseases pre-birth. It is telling that modern medicine now routinely produces hundreds of thousands of 'miracles' every single day and this will only increase that figure.

我真的不明白为什么那些替上帝担心的团体的心态，宁愿看到孩子带着先天性遗传疾病出生，而不愿意在出生前接受治愈这些疾病的技术帮助。据说现代医学每天都会产生成百上千的“奇迹”，这只会增加这个数字。

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John -> Carpejugulum
Insp. callaghan - I fail to understand your (il)logic. Of course editing the DNA and removing the defective gene will eradicate the associated genetic disease

Insp. callaghan - 我不能理解你的（非）逻辑. 编辑DNA并移除有缺陷的基因当然能够完全根除相关遗传疾病。

fewpeople -> Carpejugulum
@Insp. callaghan is an anti vaxxer i'm sure they think everything mutates and by them not helping it will just "go away"

@Insp. callaghan 是一个反对疫苗注射者，他们觉得任何东西都会突变，他们觉得这些疾病不用治疗就会好。

Poppy flanders
Some people need editing.

一些人需要这种编辑。

fewpeople
cue religion having an uneducated opinion.

这表明宗教是多么无知?